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Symbol
Name
ID

Htra2
HtrA serine peptidase 2
MGI:1928676

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Neutropenia
Disease(s) Associated with HTRA2	Neutropenia
3-methylglutaconic aciduria type 8

Mouse Phenotypes

abnormal thymus morphology

small thymus

thymus atrophy

decreased pro-B cell number

decreased double-positive T cell number

decreased pre-B cell number

decreased single-positive T cell number

decreased lymphocyte cell number

small spleen

spleen atrophy

abnormal interleukin level

abnormal tumor necrosis factor level

abnormal immune system morphology

Availability

Mouse Genotype

Htra2^mnd2/Htra2^mnd2

Htra2^tm1.2Hohj/Htra2^tm1.2Hohj

Htra2^tm1Jdo/Htra2^tm1Jdo

Htra2^tm1.1Hohj/Htra2^tm1.1Hohj
Tg(Nes-cre)1Kln/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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